October 7, 2024 Mitchell Glass President and Chief Medical Officer TNF Pharmaceuticals, Inc. 855 N. Wolfe Street, Suite 623 Baltimore, MD 21205 Re: TNF Pharmaceuticals, Inc. Form 10-K Filed April 1, 2024 File No. 001-36268 Dear Mitchell Glass: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Alla Digilova, Esq.